RELIEF FROM TOTAL PAIN Formulation Humane

Polyherbal formulation Humane has been designed with the idea of providing a long-term solution for the fight against cancer-related problems. A combination of the ancient sciences of Ayurveda and modern cannabis leaf research, Humane formulation is made up of ingredients derived from plants. Dame Cicely Saunders first articulated the theory of total pain to describe the sum of suffering (physical, spiritual, psychological, and social) experienced by patients faced with advanced disease and terminal illness (Clark, 1999).

Therapeutic Benefits of Formulation Humane

By blending Ayurveda and knowledge on Cannabis, multiple therapeutic benefits are being offered. Listed below are some of the benefits that it offers:

Relief from Total Pain

Helps to reduce Chemo caused nausea, Vomiting

Improves the efficacy of Cancer Treatment

Reduce Cancer-related complex pain

Support the Appetite and healthy weight 0' of Cancer patients.

Helps to maintain balance and general condition during cancer therapy

Helps to balance immunity

Reduce the risk of autoimmunity and hormone imbalance

Mechanisms of Action

CAUTION: Schedule E-1 drug. One tablet twice a day as per the physician’s guidance. To be taken strictly under medical supervision only.

Chronic Pain

Cannabinoids produce analgesia by acting on multiple pain targets within the peripheral and CNS by activating specific receptors throughout the body, in particular CB1 which are found predominantly in CNS and CB2 receptors found in cells involved with the immune system. Besides acting on cannabinoid CB1/CB2, they may reduce pain through interaction with the putative non-CB1/CB2 cannabinoid G protein-coupled receptors (GPCR55 or GPCR18) and opioid or serotonin (5-HT) receptors (1)

Appetite

Hunger levels are determined by a substance in the human body called ghrelin, which is known as the ‘hunger hormone’. The hormone is released by the stomach, intestines and brain, as it stimulates and manages appetite. Cannabis triggers ghrelin levels and stimulates appetite (2)

IBS, vomiting & Diarrhoea

Cannabinoids predominately mediate inhibitory pathways in the gastrointestinal tract through the reduction of vagal cholinergic tone. CB2 modulates inflammation, whereas CB1 controls central functions, including pain control, satiety, nausea, and vomiting. The distribution and concentration of the endocannabinoid system in specific tissues demonstrate the physiology of cannabinoids in the gastrointestinal tract and offer possible drug targets for the management of inflammatory bowel disease.(3)

Pathya (Preferred Diet)

Diet: Fresh, Warm, and unctuous, light, and easily digestible meals. Seasonal and regional fruits and vegetables with low salt and sugar intake or as advised by the physician.

Lifestyle: Body massage(Abhyangam) and regular body workout as per the body's strength, and early dinner that aids in a timely sleep cycle.

Apathya (To be Avoided)

Diet: Excessive spicy, cold, dry, reheated, and heavy meals with high salt and sugar intake that can vitiate Vata-Kapha in the body.

Lifestyle: Late night sleep, excessive physical and mental workout, improper diet and late dinner.